Department of Gynecology and Obstetrics, Shengjing Hospital of China Medical University, Liaoning, PRC.
J Perinatol. 2013 Feb;33(2):103-6. doi: 10.1038/jp.2012.58. Epub 2012 May 31.
To explore the significance of neonatal body indices in identifying macrosomic infants, we compared the neonatal birth weight, body length, head circumference, chest circumference, neonatal body indices, Quetelet index (QI), Kaup Index (KI), head circumference to chest circumference ratio (HC/CC) and maternal fasting blood glucose (BG) for both diabetic and healthy mothers.
This is a retrospective study of 177 macrosomic neonates, 100 having been born to normal mothers and 77 to diabetic mothers. Multiple regression analyses were done between neonatal body indices and maternal fasting BG.
Fetal QI and KI indices of macrosomic infants of diabetic mothers were higher compared with those born to healthy mothers, whereas the HC/CC was the reverse. The multiple regression equation used to compare neonatal physical development indices to maternal fasting BG was BG=6.959+0.031QI-(4.482 × HC/CC). QI and HC/CC had linear relationships to maternal fasting BG (P<0.05). As birth weight had no direct correlation with maternal fasting BG, it was not introduced into the regression equation.
Higher QI and KI along with lower HC/CC may be a predictor of macrosomia due to maternal diabetes when compared with birth weight alone.
探讨新生儿体格指数在识别巨大儿中的意义,我们比较了糖尿病母亲和健康母亲所生巨大儿的新生儿出生体重、身长、头围、胸围、新生儿体格指数、奎特利指数(QI)、考普指数(KI)、头围与胸围比(HC/CC)和母亲空腹血糖(BG)。
这是一项对 177 例巨大儿的回顾性研究,其中 100 例为正常母亲所生,77 例为糖尿病母亲所生。对新生儿体格指数与母亲空腹 BG 之间进行多元回归分析。
与健康母亲所生巨大儿相比,糖尿病母亲所生巨大儿的胎儿 QI 和 KI 指数较高,而 HC/CC 则相反。用于比较新生儿体格发育指数与母亲空腹 BG 的多元回归方程为 BG=6.959+0.031QI-(4.482 × HC/CC)。QI 和 HC/CC 与母亲空腹 BG 呈线性关系(P<0.05)。由于出生体重与母亲空腹 BG 无直接相关性,因此未引入回归方程。
与单独的出生体重相比,当由糖尿病母亲引起时,较高的 QI 和 KI 以及较低的 HC/CC 可能是巨大儿的预测指标。