Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Ophthalmologica. 2012;228(1):1-6. doi: 10.1159/000334620. Epub 2012 May 31.
To investigate the change in localization of recurrent or persistent macular edema (ME) secondary to branch retinal vein occlusion (BRVO) after a therapeutic intervention.
Twenty-six eyes of 23 patients with recurrent or persistent ME secondary to BRVO were included in this retrospective case series. We analyzed the distance between the fovea and the top of the ME (fovea-ME top distance) and the ME area using optical coherence tomography before treatment and when ME recurred or persisted.
The fovea-ME top distance decreased from 1.8 ± 1.6 to 1.2 ± 1.3 mm (p = 0.008). The ME area also decreased from 11.9 ± 4.9 to 7.6 ± 5.0 mm(2) (p = 0.0003). The retinal vascular leakage area correlated with the ME area in all eyes.
The site of recurrent or persistent ME tends to shift toward the fovea. These results suggest that residual perifoveal vascular leakage might be the predominant cause of recurrent or persistent ME.
探讨视网膜分支静脉阻塞（BRVO）继发复发性或持续性黄斑水肿（ME）的定位变化。
本回顾性病例系列研究纳入了 23 例 26 只眼复发性或持续性 ME 继发于 BRVO 的患者。我们使用光学相干断层扫描（OCT）分析治疗前和 ME 复发或持续时黄斑中心凹与 ME 顶部之间的距离（黄斑中心凹至 ME 顶部的距离）和 ME 面积。
黄斑中心凹至 ME 顶部的距离从 1.8±1.6mm 减小至 1.2±1.3mm（p=0.008）。ME 面积也从 11.9±4.9mm²减小至 7.6±5.0mm²（p=0.0003）。所有眼的视网膜血管渗漏面积与 ME 面积相关。
复发性或持续性 ME 的部位倾向于向黄斑中心凹移动。这些结果表明，残留的中心凹旁血管渗漏可能是复发性或持续性 ME 的主要原因。
