Creighton S M, Stanton S L
Department of Obstetrics and Gynaecology, St George's Hospital, London.
Br J Urol. 1990 Dec;66(6):613-4. doi: 10.1111/j.1464-410x.1990.tb07192.x.
Patients with symptoms of frequency and urgency often complain that their symptoms are exacerbated by tea or coffee. A series of 20 women with confirmed detrusor instability and 10 asymptomatic women were given 200 mg of caffeine citrate and urodynamic studies were performed. In the group with detrusor instability there was a statistically significant increase in detrusor pressure on bladder filling following administration of caffeine, but no difference in volume at first contraction, height of contraction or bladder capacity. Normal women had no abnormality on cystometry.
有尿频和尿急症状的患者常常抱怨称，茶或咖啡会加重他们的症状。对20名确诊为逼尿肌不稳定的女性和10名无症状女性进行了一项研究，给她们服用200毫克柠檬酸咖啡因，然后进行尿动力学研究。在逼尿肌不稳定组中，服用咖啡因后膀胱充盈时逼尿肌压力有统计学意义的显著增加，但首次收缩时的尿量、收缩高度或膀胱容量没有差异。正常女性膀胱测压无异常。
