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在儿科急诊科对浅表皮肤脓肿切开引流术后伤口填塞与不进行伤口填塞进行比较的随机试验。

Randomized trial comparing wound packing to no wound packing following incision and drainage of superficial skin abscesses in the pediatric emergency department.

作者信息

Kessler David O, Krantz Amanda, Mojica Michael

机构信息

Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.

出版信息

Pediatr Emerg Care. 2012 Jun;28(6):514-7. doi: 10.1097/PEC.0b013e3182587b20.

DOI:10.1097/PEC.0b013e3182587b20
PMID:22653459
Abstract

OBJECTIVE

The objective of this study was to investigate the impact of wound packing versus no wound packing on short-term failure rates and long-term recurrences after incision and drainage (I&D) of a simple cutaneous abscess.

METHODS

In this randomized, single-blind, prospective study, subjects between the ages 1 and 25 years with skin abscesses needing an I&D were enrolled consecutively and randomized to be packed or not packed following the procedure. Treatment failure was assessed at a 48-hour follow-up visit by a masked observer who rated the need for a major intervention (repeat I&D or re-exploration) or minor intervention (antibiotics initiated or changed, need for packing, or repeat visit). Pain scores were assessed using color analog scales before and after the procedure and repeated at the 48-hour follow-up visit. Healing and abscess recurrence were assessed via telephone interview at 1 week and 1 month.

RESULTS

Fifty-seven subjects were enrolled over a 15-month period. Overall failure rates were similar between the groups, with 19 (70%) of 27 subjects in the packed group needing an intervention by 48 hours compared with 13 (59%) of 22 subjects in the nonpacked group who needed an intervention (difference, 11%; 95% confidence interval, -15% to 36%). Major and minor intervention rates were also similar. Pain scores did not significantly differ between groups.

CONCLUSIONS

Wound packing does not appear to significantly impact the failure or recurrence rates after simple I&D. Larger studies are needed to better validate the equivalency of these 2 strategies.

摘要

目的

本研究旨在探讨伤口填塞与不进行伤口填塞对单纯性皮肤脓肿切开引流(I&D)术后短期失败率和长期复发率的影响。

方法

在这项随机、单盲、前瞻性研究中,连续纳入年龄在1至25岁之间需要进行I&D的皮肤脓肿患者,并在手术后随机分为进行填塞组或不进行填塞组。由一名盲法观察者在48小时随访时评估治疗失败情况,该观察者对是否需要进行重大干预(重复I&D或再次探查)或轻微干预(开始或更换抗生素、需要填塞或再次就诊)进行评分。在手术前后使用彩色模拟量表评估疼痛评分,并在48小时随访时重复评估。在1周和1个月时通过电话访谈评估愈合情况和脓肿复发情况。

结果

在15个月的时间里共纳入了57名受试者。两组的总体失败率相似,填塞组27名受试者中有19名(70%)在48小时内需进行干预,而非填塞组22名受试者中有13名(59%)需要进行干预(差异为11%;95%置信区间为-15%至36%)。重大和轻微干预率也相似。两组之间的疼痛评分无显著差异。

结论

伤口填塞似乎对单纯I&D术后的失败率或复发率没有显著影响。需要进行更大规模的研究以更好地验证这两种策略的等效性。

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