Taal B G, ten Bokkel Huinink W W, Simonetti G, Franklin H, McVie J G
Department of Gastroenterology, The Netherland Cancer Institute, Amsterdam.
Cancer Invest. 1990;8(5):501-4. doi: 10.3109/07357909009012074.
Twenty-one patients with advanced gastric adenocarcinoma were treated with a combination chemotherapy schedule of sequential methotrexate and 5-fluorouracil alternated with 4-epidoxorubicin and cisplatin. This scheme was active, with 7 partial responses leading to a response rate of 33% (+/- 20%). In two cases the tumor became operable. No severe toxicity developed and the treatment was usually well tolerated.
21例晚期胃腺癌患者接受了甲氨蝶呤和5-氟尿嘧啶序贯联合化疗方案，该方案与表柔比星和顺铂交替使用。该方案具有活性，7例部分缓解，缓解率为33%（±20%）。2例患者的肿瘤变得可切除。未出现严重毒性，治疗通常耐受性良好。
