Weill Cornell Medical College.
Blood. 2012 May 31;119(22):5064-5. doi: 10.1182/blood-2012-04-418590.
I have always been puzzled by the ability of normal erythroid cells to produce a stoichiometric amount of α- and β-globin chains in the absence of cross-talk mechanisms that would control and normalize the relative rate of expression of the genes encoding these proteins.
我一直对正常红细胞在缺乏交叉对话机制的情况下能够产生等量的α-和β-球蛋白链的能力感到困惑,这种机制可以控制和规范编码这些蛋白质的基因的相对表达速率。