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产前诊断为口腔和颈部畸形的胎儿的宫外产时治疗(EXIT手术)麻醉:病例报告

Anesthesia for ex utero intrapartum treatment (EXIT procedure) in fetus with prenatal diagnosis of oral and cervical malformations: case reports.

作者信息

Helfer Daniel Corrêa, Clivatti Jefferson, Yamashita Américo Massafuni, Moron Antonio Fernades

机构信息

Department of Anesthesiology, Pain and Intensive Care, Universidade Federal de São Paulo-Escola Paulista de Medicina (UNIFESP-EPM), Vila Clementino, São Paulo, SP, Brazil.

出版信息

Rev Bras Anestesiol. 2012 May-Jun;62(3):411-23. doi: 10.1016/S0034-7094(12)70141-1.

Abstract

BACKGROUND AND OBJECTIVES

Fetus prenatally diagnosed with neck tumors, or with any other disease that obstructs the airways, should not be treated conventionally, as the assistant physician has to face two challenges right after the infant's delivery: the limited time to establish the access to the potentially difficult airways and the lack of anesthesia of the neonate in case of instrumentation of the airways. The ex utero intrapartum treatment, i.e., the EXIT procedure consists of maintaining the fetoplacental circulation during the cesarean section, until the airways of the fetus be secured.

CASE REPORTS

Female patient, 37 years old, G3P2, 38 weeks pregnant, having polyhydramnios and fetus diagnosed with large cervical masses by prenatal ultrasound. A cesarean section was performed using the EXIT procedure to enable safe access to the infant's airways. After hysterotomy, the fetus was intubated by direct laryngoscopy. The neonate was immediately transferred to another operating room, where cervical tumor resection of the neck tumor and tracheostomy were successfully performed. Female patient, 27 years old, G3P1A1, 32 weeks pregnant, whose fetus was prenatally diagnosed with a large oral tumor. As the tumor obstructed the fetus' airways, a tracheostomy was performed when the fetus underwent EXIT procedure. It was then possible to use direct laryngoscopy for neonate intubation. The fetus underwent tumor resection and was sent to the Neonatal Intensive Care Unit.

CONCLUSIONS

Reports describe the successful use of general anesthesia with isoflurane for cesarean delivery followed by the EXIT procedure in fetus diagnosed with tumors obstructing the airways.

摘要

背景与目的

产前诊断出颈部有肿瘤或患有其他任何阻塞气道疾病的胎儿,不应采用常规治疗,因为助理医师在婴儿出生后必须面对两大挑战:建立通往可能存在困难气道的通道时间有限,以及在进行气道插管时新生儿缺乏麻醉。子宫外产时处理(EXIT)程序,即在剖宫产过程中维持胎儿 - 胎盘循环,直至确保胎儿气道安全。

病例报告

37岁女性患者,孕3产2,妊娠38周,羊水过多,产前超声诊断胎儿颈部有巨大肿块。采用EXIT程序进行剖宫产,以便安全进入婴儿气道。子宫切开术后,通过直接喉镜对胎儿进行插管。新生儿立即被转至另一手术室,在那里成功进行了颈部肿瘤切除及气管造口术。27岁女性患者,孕3产1流1,妊娠32周,其胎儿产前诊断为巨大口腔肿瘤。由于肿瘤阻塞胎儿气道,在胎儿接受EXIT程序时进行了气管造口术。随后得以使用直接喉镜对新生儿进行插管。胎儿接受肿瘤切除后被送往新生儿重症监护病房。

结论

报告描述了对诊断出气道阻塞性肿瘤的胎儿,在剖宫产时成功使用异氟烷全身麻醉并随后进行EXIT程序的情况。

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