Lurie S
Department of Obstetrics and Gynecology, Kaplan Hospital, Rehovot, Israel.
Gynecol Obstet Invest. 1990;30(3):147-9. doi: 10.1159/000293245.
The age population distribution of erythrocytes in late pregnancy was evaluated by the volume and density distribution of cells. This approach enables an evaluation of the life span of erythrocytes in the circulation without using radioactive elements. A younger cell population was found in the circulation of women in late pregnancy as compared to nonpregnant women of similar ages, which might be indicative of shortened life span of erythrocytes. This shortened life span might be explained by the fact that erythrocytes made under conditions of increased erythropoiesis and/or increased metabolic rate show acceleration of senescence. This indication of reduced life span of the erythrocytes in late pregnancy may contribute to the understanding of the increased erythropoiesis on the one hand, and reduced hemoglobin concentration on the other hand, which often occurs in late pregnancy.
通过细胞体积和密度分布评估妊娠晚期红细胞的年龄分布。这种方法能够在不使用放射性元素的情况下评估循环中红细胞的寿命。与年龄相仿的未孕女性相比，妊娠晚期女性循环中的细胞群体更年轻，这可能表明红细胞寿命缩短。这种缩短的寿命可能是由于在红细胞生成增加和/或代谢率增加的条件下生成的红细胞衰老加速。妊娠晚期红细胞寿命缩短这一迹象一方面可能有助于理解红细胞生成增加，另一方面可能有助于理解妊娠晚期经常出现的血红蛋白浓度降低。
