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Churg-Strauss 综合征,一种罕见的颅内出血病因。

Churg-Strauss, a rare cause of intracerebral haemorrhage.

机构信息

Department of Neurosurgery, Salford Royal NHS Foundation Trust, Stott Lane, Salford M6 8HD, UK.

出版信息

J Clin Neurosci. 2012 Aug;19(8):1177-8. doi: 10.1016/j.jocn.2012.01.006. Epub 2012 May 31.

DOI:10.1016/j.jocn.2012.01.006
PMID:22658240
Abstract

Intracerebral haemorrhage (ICH) is a common and devastating condition. We describe a 43-year-old man with the rare Churg-Strauss syndrome, which was diagnosed after he presented with an ICH. He was managed initially neurosurgically with clot evacuation and craniectomy. Post-investigation and diagnosis of Churg-Strauss, treatment was with high dose methylprednisolone (then oral prednsiolone) and intravenous cyclophosphamide. Clinicians should be aware that Churg-Strauss syndrome can, rarely, be a cause of ICH. Given its high morbidity and mortality, it is important that patients are diagnosed promptly and managed appropriately.

摘要

脑出血(ICH)是一种常见且严重的疾病。我们描述了一位 43 岁的男性,他患有罕见的变应性肉芽肿性血管炎(Churg-Strauss 综合征),该疾病在他因脑出血就诊后被诊断出来。他最初接受了神经外科手术治疗,包括清除血肿和颅骨切除术。在进行调查并诊断出 Churg-Strauss 综合征后,给予大剂量甲基泼尼松龙(随后口服泼尼松)和静脉注射环磷酰胺治疗。临床医生应该意识到,Churg-Strauss 综合征很少会导致脑出血。鉴于其高发病率和死亡率,及时诊断和适当治疗非常重要。

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