通过等电聚焦法进行血清类黏蛋白（ORM）分型：ORM单倍型分析
Orosomucoid (ORM) typing by isoelectric focusing: an analysis of ORM haplotypes.
作者信息
Yuasa I, Umetsu K, Suenaga K, Iha M, Hirata H, Ikebuchi J
机构信息
Department of Legal Medicine, Tottori University School of Medicine, Yonago, Japan.
出版信息
Hum Hered. 1990;40(5):267-71. doi: 10.1159/000153943.
A new separator isoelectric focusing method for typing of orosomucoid (ORM) was developed. This method provided a superior resolution of ORM patterns: two close bands of ORM15.2 products were clearly separated. A total of 364 subjects from Okinawa (Japan) were classified into 21 ORM phenotypes determined by 6 ORM1 and 7 ORM2 alleles including a polymorphic silent allele, ORM2QO, and 2 new rare variants, ORM218 and ORM219. These phenotypes were also explained by 12 ORM haplotypes, half of which were polymorphic.
开发了一种用于血清类黏蛋白（ORM）分型的新型等电聚焦分离方法。该方法能提供更高分辨率的ORM图谱：ORM15.2产物的两条紧密条带被清晰分离。来自日本冲绳的364名受试者被分为21种ORM表型，这些表型由6个ORM1等位基因和7个ORM2等位基因决定，其中包括一个多态性沉默等位基因ORM2QO以及2个新的罕见变体ORM218和ORM219。这些表型也可用12种ORM单倍型来解释，其中一半是多态性的。
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