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机器人辅助腹腔镜部分肾切除术:在一家高容量机构的分步当代技术和手术结果。

Robot-assisted laparoscopic partial nephrectomy: step-by-step contemporary technique and surgical outcomes at a single high-volume institution.

机构信息

Section of Laparoscopic and Robotic Surgery, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

出版信息

Eur Urol. 2012 Sep;62(3):553-61. doi: 10.1016/j.eururo.2012.05.021. Epub 2012 May 29.

DOI:10.1016/j.eururo.2012.05.021
PMID:22658759
Abstract

BACKGROUND

Robotic technology is being increasingly adopted in urologic surgery.

OBJECTIVE

To describe a contemporary surgical technique and report cumulative surgical outcomes of robot-assisted laparoscopic partial nephrectomy (RALPN) at our tertiary care institution.

DESIGN, SETTING, AND PARTICIPANTS: Medical charts of consecutive patients who underwent RALPN between June 2006 and November 2011 were reviewed from a prospectively maintained, institutional review board-approved database.

SURGICAL PROCEDURE

The main steps of our current surgical technique are described in this video tutorial: patient positioning and trocar placement; bowel mobilization; hilar dissection; tumor identification and demarcation; clamping of the hilum; tumor excision; renorraphy; hilar unclamping; and tumor retrieval.

OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS

Patients' characteristics and main surgical outcomes were analyzed.

RESULTS AND LIMITATIONS

A total of 400 patients (mean age: 58.5 yr, mean body mass index: 30.7 kg/m(2)) were included in this analysis. Mean renal tumor size was 3.17 cm (standard deviation [SD]: 1.64) and mean RENAL score was 7.2 (SD: 2). Six patients (1.5%) presented with a solitary kidney. Mean total operative time was 190.3 min (SD: 57), and mean warm ischemia time was 19.2 min (SD: 10.72). In 36 cases (9%), an unclamped hilum technique was used. After a mean follow-up of 12.4 mo (SD: 12.2), there was a decline of -9.2 ml/min per 1.73 m(2) (SD: 26.56) in estimated glomerular filtration rate. Most renal masses were malignant (74.5%), and the overall mean tumor size was 3.05 cm (SD: 1.66). Renal cell carcinoma with a clear cell histology represented the most frequent malignant diagnosis (64.4% of cases). A positive margin was observed in nine cases (2.25%). A total of 11 intraoperative complications (2.7%) occurred, and a conversion to open or laparoscopic PN was required in six cases (1.5%). A postoperative complication occurred in 61 cases (15.3%), the majority of them being low grade.

CONCLUSIONS

The standardization of each surgical step has allowed for optimization of RALPN and ultimately improved its outcomes and expanded its indications.

摘要

背景

机器人技术在泌尿科手术中越来越多地被采用。

目的

描述一种现代手术技术,并报告我们的三级护理机构中机器人辅助腹腔镜部分肾切除术(RALPN)的累积手术结果。

设计、设置和参与者:从一个前瞻性维护的机构审查委员会批准的数据库中回顾了 2006 年 6 月至 2011 年 11 月期间接受 RALPN 的连续患者的病历。

手术步骤

本视频教程介绍了我们当前手术技术的主要步骤:患者体位和套管放置;肠管移动;肾门解剖;肿瘤识别和划定;肾门夹闭;肿瘤切除;肾缝合;肾门松解;肿瘤取出。

结果和局限性

本分析共纳入 400 例患者(平均年龄:58.5 岁,平均体重指数:30.7kg/m2)。平均肾肿瘤大小为 3.17cm(标准差[SD]:1.64),平均 RENAL 评分为 7.2(SD:2)。6 例患者(1.5%)为孤立肾。平均总手术时间为 190.3 分钟(SD:57),平均热缺血时间为 19.2 分钟(SD:10.72)。36 例(9%)采用未夹闭肾门技术。平均随访 12.4 个月(SD:12.2)后,估算肾小球滤过率下降-9.2ml/min/1.73m2(SD:26.56)。大多数肾肿瘤为恶性(74.5%),总体平均肿瘤大小为 3.05cm(SD:1.66)。透明细胞组织学的肾细胞癌占最常见的恶性诊断(64.4%的病例)。9 例(2.25%)发现切缘阳性。共发生 11 例术中并发症(2.7%),6 例(1.5%)需要转为开放或腹腔镜 PN。61 例(15.3%)发生术后并发症,大多数为低级别。

结论

每个手术步骤的标准化都使 RALPN 得以优化,并最终改善了其结果并扩大了其适应证。

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