[肾酶与心血管疾病的研究进展]
[Research progress with renalase and cardiovascular disease].
作者信息
Guo Yunzhong, Jiang Weihong
机构信息
Department of Cardiology, Central South University, Changsha, China.
出版信息
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2012 May;37(5):537-40. doi: 10.3969/j.issn.1672-7347.2012.05.021.
Abstract
Renalase, a novel amine oxidase, is secreted by kidney. It regulates heart function and blood pressure by degrading catecholamines. Hormones secreted by the kidney are associated with cardiovascular disease. Renalase, as a new biomarker of heart and kidney functional correlation, can lower blood pressure, protect ischemic heart muscle, improve heart function and degrade catecholamine.
摘要
肾酶是一种新型胺氧化酶，由肾脏分泌。它通过降解儿茶酚胺来调节心脏功能和血压。肾脏分泌的激素与心血管疾病有关。肾酶作为心脏和肾脏功能相关性的一种新生物标志物，可降低血压、保护缺血心肌、改善心脏功能并降解儿茶酚胺。
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