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心外腔 Fontan 手术与直接腔肺连接:中期结果。

Extracardiac Fontan with direct cavopulmonary connections: midterm results.

机构信息

Heart Center, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, China.

出版信息

Eur J Cardiothorac Surg. 2013 Feb;43(2):318-23. doi: 10.1093/ejcts/ezs288. Epub 2012 Jun 1.

Abstract

OBJECTIVES

The aim of this study was to analyse the midterm results following superior and inferior direct cavopulmonary connections (DCPC) to create a Fontan circulation in patients with functionally univentricular hearts.

METHODS

A retrospective review of patients operated on between January 2005 and December 2011 was carried out.

RESULTS

Thirty consecutive patients who underwent this type of operation were retrospectively reviewed. There were 18 (60%) males and 12 (40%) females, with a median age of 69 months (range 16-150 months) and median weight of 23 kg (range 11-46 kg). Aortic cross-clamping was used in 10 patients, with a median cross-clamp time of 40 min (range 23-99) and a median cardiopulmonary bypass (CPB) time of 135 min (range 76-179 min). The remaining 20 patients were operated on without aortic cross-clamping. Their median CPB time was 104 min (range 78-139 min). Fenestration was performed in 16 patients. The associated intracardiac procedures were performed in 10 patients. The follow-up period ranged from 2 months to 6 years. Operative mortality and late mortality after discharge was zero. The major postoperative complications included supraventricular tachycardia in one patient, oliguria and peritoneal dialysis in one and chest drainage (>30 ml/day) persisting >7 days in five (20%). One patient developed sinus bradycardia in association with sinus pauses 2 months after discharge. One patient developed pericardial effusion 1 month after discharge. A computational fluid dynamic study was performed in one patient. The computational fluid dynamic study showed that DCPC may have a better power efficiency.

CONCLUSIONS

Superior and inferior DCPCs to create a Fontan circulation in appropriately selected patients with functionally univentricular hearts can be performed with a low risk and a low rate of reinterventions. The midterm results are favourable.

摘要

目的

本研究旨在分析功能性单心室患者行上、下腔直接心腔吻合(DCPC)构建 Fontan 循环的中期结果。

方法

对 2005 年 1 月至 2011 年 12 月期间行此类手术的患者进行回顾性分析。

结果

回顾性分析 30 例连续接受该手术的患者。其中男 18 例(60%),女 12 例(40%),中位年龄 69 个月(16-150 个月),中位体重 23kg(11-46kg)。10 例患者行主动脉阻断,中位阻断时间 40min(23-99min),中位体外循环(CPB)时间 135min(76-179min)。其余 20 例患者行非主动脉阻断手术,中位 CPB 时间 104min(78-139min)。16 例患者行开窗术。10 例患者行心内合并手术。随访时间 2 个月至 6 年。无手术死亡及出院后晚期死亡。主要术后并发症包括 1 例患者出现室上性心动过速,1 例患者少尿并接受腹膜透析,5 例(20%)患者持续胸管引流量>30ml/d>7 天。1 例患者出院后 2 个月出现窦性心动过缓并窦性停搏。1 例患者出院后 1 个月出现心包积液。1 例患者行计算流体动力学研究。该研究显示 DCPC 构建 Fontan 循环可能具有更好的动力效率。

结论

在适当选择的功能性单心室患者中行上、下腔 DCPC 构建 Fontan 循环可获得较低的风险和较低的再干预率,中期结果良好。

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