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[升主动脉及主动脉弓重建术后纵隔炎及移植物感染的成功治疗报告]

[A report of successful treatment of mediastinitis and graft infection after ascending and aortic arch reconstruction].

作者信息

Harakawa I, Nakajima N, Ando M, Adachi S, Takeuchi S, Fujita T

机构信息

Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1990 Oct;38(10):2112-6.

PMID:2266286
Abstract

A 43 years old male patient had composite graft replacement of ascending aorta and aortic arch with total reconstruction for his aortic valve regurgitation and ascending and aortic arch aneurysm. He developed high fever leucocytosis and in the early postoperative period and was diagnosed as aorta mediastinitis by proving bacterial culture positive in blood as well as in the drainage fluid. Re-exploration of mediastinal cavity was carried out and the necrotic tissues were removed as much as possible. The mediastinal cavity, especially around the graft was also thoroughly irrigated and washed with Iodine (Isozin) solution. Following this, mediastinal cavity was packed with non-diluted solution of Iodine sponge. Thereafter mediastinum was left open by applying sprint and patient was brought back to ICU. He was kept controlled ventilation and deep sedation. Mediastinal cavity was irrigated and re-packed with same solution every 8 hours for the following 48 hours so as to expect complete disinfection of the mediastinal cavity. He was brought back to the operation room again and midsternal incision was extended to the abdomen. Half portion of the major omentum was isolated from the stomach and transplanted into the mediastinal cavity with its vascular supply. Special care was taken to wrap around the graft with omentum. The sternum and skin were closed without any drainage tube. As postoperative complications most probably related to the application of high concentration of Iodine solution, he developed severe hepatic failure for which he was treated with hemofiltration. This was gradually improved and the infection was well controlled. He was discharged from the hospital on the 77th postoperative day.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

一名43岁男性患者因主动脉瓣反流、升主动脉及主动脉弓动脉瘤接受了升主动脉和主动脉弓复合移植物置换及全重建手术。术后早期他出现高热、白细胞增多,血及引流液细菌培养阳性,被诊断为主动脉纵隔炎。进行了纵隔再次探查,尽可能清除坏死组织。纵隔腔,尤其是移植物周围,也用碘(异索金)溶液彻底冲洗。之后,纵隔腔用未稀释的碘海绵溶液填充。然后,通过应用胸带使纵隔保持开放,患者被送回重症监护病房。给予其控制通气和深度镇静。在接下来的48小时内,每8小时用相同溶液冲洗并重新填充纵隔腔,以期纵隔腔完全消毒。再次将患者送回手术室,将胸骨正中切口延伸至腹部。从胃分离出一半大网膜,将其带血管蒂移植到纵隔腔。特别注意用大网膜包裹移植物。关闭胸骨和皮肤,未留置任何引流管。由于术后并发症很可能与高浓度碘溶液的应用有关,他出现了严重肝功能衰竭,为此接受了血液滤过治疗。肝功能逐渐改善,感染得到良好控制。术后第77天他出院了。(摘要截短至250字)

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