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小切口小脑扁桃体切除术联合枕下减压及硬脑膜成形术治疗Chiari I型畸形(合并脊髓空洞症):76例手术治疗患者的长期随访

Cerebellar tonsillectomy with suboccipital decompression and duraplasty by small incision for Chiari I malformation (with syringomyelia): long term follow-up of 76 surgically treated cases.

作者信息

Ma Junpeng, You Chao, Chen Haifeng, Huang Siqing, Ieong Chengcheng

机构信息

West China Hospital, Department of Neurosurgery, P. R. China.

出版信息

Turk Neurosurg. 2012;22(3):274-9. doi: 10.5137/1019-5149.JTN.4634-11.1.

Abstract

AIM

To explore the surgical effect of cerebellar tonsillectomy with suboccipital decompression and duraplasty by small surgical incision (3~4cm around the foramina magnum) on treating Chiari I Malformation (CM I) patients.

MATERIAL AND METHODS

A retrospective study was undertaken on 76 CM I patients treated by this surgery. The surgical efficacy on clinical symptoms and syringomyelia were overall evaluated and analyzed.

RESULTS

The study included 76 cases (36 men and 40 women; age range, 5-58 years; mean age at surgery, 38.8 years). Preoperative MRI confirmed 56 cases associated with syringomyelia. The follow-up period ranged from 25 to 58 months (median, 46 months). At the end of follow-up, 61 patients (80.26%) had improved, 12 patients (15.79%) were stabilized, and 3 patients (3.95%) had worsened. In MRI scan, syrinx of 55 patients (98.21%) had improved or stabilized compare with syrinx growth in only one patient (1.79%). Statistical analysis reveal the surgical effect tend to be much better in patients with short duration of preoperative symptoms (P=0.001).

CONCLUSION

Cerebellar tonsillectomy with suboccipital decompression and duraplasty can provide long-time cure for most CM I cases. Early diagnosis and surgery is necessary to improve the surgical effect. A 3~4cm incision around foramen magnum is enough for these operations and may be conducive to reduce postoperative complications.

摘要

目的

探讨经枕下小切口(枕骨大孔周围3~4厘米)行小脑扁桃体切除术并枕下减压及硬脑膜成形术治疗Chiari I型畸形(CM I)患者的手术效果。

材料与方法

对76例行此手术治疗的CM I患者进行回顾性研究。对临床症状和脊髓空洞症的手术疗效进行全面评估和分析。

结果

该研究纳入76例患者(男36例,女40例;年龄范围5~58岁;手术时平均年龄38.8岁)。术前MRI证实56例合并脊髓空洞症。随访时间为25至58个月(中位数为46个月)。随访结束时,61例患者(80.26%)病情改善,12例患者(15.79%)病情稳定,3例患者(3.95%)病情恶化。在MRI扫描中,55例患者(98.21%)的空洞有所改善或稳定,仅1例患者(1.79%)的空洞增大。统计分析显示术前症状持续时间短的患者手术效果往往更好(P = 0.001)。

结论

小脑扁桃体切除术并枕下减压及硬脑膜成形术可为大多数CM I病例提供长期治愈效果。早期诊断和手术对于提高手术效果很有必要。枕骨大孔周围3~4厘米的切口对于这些手术已足够,且可能有助于减少术后并发症。

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