Süsal Caner, Opelz Gerhard
Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany.
Methods Mol Biol. 2012;882:267-77. doi: 10.1007/978-1-61779-842-9_15.
The Collaborative Transplant Study (CTS) was initiated in 1982 in Heidelberg, Germany, and originated from the need to gain further insight into the complex problems and risks involved in human organ transplantation. Currently, more than 400 transplant centers in 45 countries are contributing to this voluntary international effort, and from the beginning of the study, the impact on graft outcome of immunological factors, such as matching for HLA antigens and allosensitization to HLA and non-HLA antigens, have been areas of interest. Herein, we summarize the recent findings from the CTS on these two topics.
协作移植研究（CTS）于1982年在德国海德堡启动，源于需要进一步深入了解人体器官移植中涉及的复杂问题和风险。目前，45个国家的400多个移植中心参与了这项自愿性国际工作，自研究开始以来，免疫因素对移植结果的影响，如HLA抗原配型以及对HLA和非HLA抗原的同种致敏，一直是研究的重点领域。在此，我们总结了CTS在这两个主题上的最新研究结果。
