Stasiak Mark E, Wiznia Dan, Alzoobaee Saif, Ciccotti Michael C, Imhauser Carl W, Voigt Clifford, Torzilli Peter A, Deng Xiang-Hua, Rodeo Scott A
Hospital for Special Surgery, New York, NY 10021, USA.
J Biomech Eng. 2012 Apr;134(4):041008. doi: 10.1115/1.4006341.
We designed and validated a novel device for applying flexion-extension cycles to a rat knee in an in vivo model of anterior cruciate ligament reconstruction (ACL-R). Our device is intended to simulate rehabilitation motion and exercise post ACL-R to optimize physical rehabilitation treatments for the improved healing of tendon graft ligament reconstructions. The device was validated for repeatability of the knee kinematic motion by measuring the force versus angular rotation response from repeated trials using cadaver rats. The average maximum force required for rotating an ACL reconstructed rat knee through 100 degrees of flexion-extension was 0.4 N with 95% variability for all trials within ±0.1 N.
我们设计并验证了一种新型装置，用于在体内前交叉韧带重建（ACL-R）模型中对大鼠膝关节施加屈伸循环。我们的装置旨在模拟ACL-R后的康复运动和锻炼，以优化物理康复治疗，促进肌腱移植韧带重建的更好愈合。通过测量使用尸体大鼠进行的重复试验中的力与角旋转响应，验证了该装置膝关节运动学运动的可重复性。使ACL重建的大鼠膝关节进行100度屈伸旋转所需的平均最大力为0.4 N，所有试验的95%变异性在±0.1 N范围内。
