Division of Allergy, Asthma and Immunology, Thomas Jefferson University, Nemours A.I. duPont Hospital for Children, 1600 Rockland Road, Wilmington, DE 19803, USA.
Clin Rev Allergy Immunol. 2013 Jun;44(3):208-28. doi: 10.1007/s12016-012-8314-2.
Integrative medicine is a relatively new discipline which attempts to combine allopathic medicine with alternative or complementary medicine, to reap the benefits of both forms of medicine in optimizing the care of patients. Integrative medicine concentrates on treating the patient as a whole, both in body and mind. While the scientific method and "evidence-based" clinical research drives the management and treatment of diseases in conventional Western medicine, alternative or complementary medicine is based on unproven yet potentially beneficial techniques that have been developed throughout history, dating back to the ancient cultures in the Middle East, Africa, and China. In spite of the lack of evidence of most alternative medicine techniques, these methodologies have been practiced for centuries with great acceptance in many countries. It is in the Western world, where "modern" medicine is dictated by the scientific method, that the most controversy in the use of these alternative modes of therapy exists. Since the science behind alternative medicine is incomplete or non-existent, it is difficult for those trained in Western medicine to accept or adopt this approach. But perhaps it is the failure of Western medicine to adequately guarantee our well being and good health that have led to the ongoing debate between the medical profession and the general public as to the benefits of these alternative treatments. In one sense, integrative medicine may be a futile attempt to coin a new term in the hope of legitimizing alternative medicine. On the other hand, there is a wealth of historical experience in the use of the techniques. Studies to evaluate the scientific basis behind ancient medical techniques are ongoing, and it is to be expected that the results will neither be uniformly positive nor negative. Of particular interest is the effect of traditional medicine, herbal formulations, and manipulative techniques on the immune system, and its application in the treatment of autoimmune and allergic diseases. Studies are being designed or conducted to investigate immune effects of herbal formulations or their components. Herbal plants or medicines may lead to skewing of the Th1/Th2 balance in either direction, thus may offer potential application in the treatment of allergic or autoimmune diseases.
整体医学是一门相对较新的学科,试图将对抗疗法与替代或补充医学相结合,以从这两种医学形式中获益,从而优化患者的护理。整体医学专注于将患者作为一个整体进行治疗,包括身体和心理。虽然科学方法和“基于证据”的临床研究推动了传统西医学对疾病的管理和治疗,但替代或补充医学则基于历史上发展起来的未经证实但具有潜在益处的技术,这些技术可以追溯到中东、非洲和中国的古代文化。尽管大多数替代医学技术缺乏证据,但这些方法在许多国家已经实践了几个世纪,并得到了广泛的认可。正是在以科学方法为主导的西方世界,这些替代治疗模式的使用才存在最大的争议。由于替代医学背后的科学不完整或不存在,受过西方医学训练的人很难接受或采用这种方法。但也许正是西方医学未能充分保证我们的健康和良好状态,导致了医学界和公众之间关于这些替代疗法益处的持续争论。从某种意义上说,整体医学可能是试图创造一个新术语,以希望使替代医学合法化。另一方面,这些技术的使用有着丰富的历史经验。评估古代医学技术背后的科学基础的研究正在进行中,可以预料的是,这些研究结果既不会完全是肯定的,也不会完全是否定的。特别值得关注的是传统医学、草药配方和手法技术对免疫系统的影响,以及它们在治疗自身免疫和过敏疾病中的应用。目前正在设计或进行研究,以调查草药配方或其成分的免疫效应。草药植物或药物可能会导致 Th1/Th2 平衡向任一方向倾斜,从而可能为治疗过敏或自身免疫性疾病提供潜在应用。