Sidransky E, Black S H, Soenksen D M, Jones S L, Dorfmann A D, Schulman J D
Genetics & IVF Institute, Fairfax, VA 22031.
Prenat Diagn. 1990 Sep;10(9):583-6. doi: 10.1002/pd.1970100906.
Chorionic villus sampling (CVS) with either transcervical catheters or transabdominal needles is a widely-accepted method for prenatal diagnosis. However, there exists a small subset of patients in whom sampling is difficult or impossible with either route because of individual anatomic variations. A new method of chorionic villus biopsy has been developed to circumvent these problems, utilizing transvaginal chorionic needle aspiration guided by an intravaginal ultrasound probe. This technique was performed successfully in 15 patients in whom villi could not be obtained by either of the conventional methods. This method now makes CVS possible in essentially all women regardless of their uterine anatomy or placental placement; it may also prove useful for very early chorionic sampling.
经宫颈导管或经腹穿刺针进行绒毛取样（CVS）是一种广泛接受的产前诊断方法。然而，由于个体解剖变异，有一小部分患者通过这两种途径进行取样都很困难或无法取样。一种新的绒毛活检方法已经开发出来以解决这些问题，该方法利用经阴道超声探头引导经阴道绒毛针吸取。这项技术在15例通过常规方法无法获取绒毛的患者中成功实施。这种方法现在基本上使所有女性都能进行绒毛取样，无论其子宫解剖结构或胎盘位置如何；它也可能被证明对极早期绒毛取样有用。
