砷暴露相关的格林-巴利综合征样神经病。
A Guillain-Barré syndrome-like neuropathy associated with arsenic exposure.
机构信息
Department of Neurology, Ulsan University Hospital, University of Ulsan College of Medicine, Republic of Korea.
出版信息
J Occup Health. 2012;54(4):344-7. doi: 10.1539/joh.12-0023-cs. Epub 2012 May 29.
OBJECTIVES
We report on a patient presenting with an isolated polyneuropathy mimicking Guillain-Barré syndrome (GBS) associated with arsenic exposure.
CASE
A 43-year-old man visited our emergency room complaining of progressive quadriparesis over the prior 5 days. His clinical course with laboratory data was typical of GBS. However, because of his recent use of herbal medication, we screened for the presence of several heavy metals. Serial analyses of urinary inorganic arsenic concentrations confirmed exposure to arsenic. He was diagnosed as arsenic neuropathy mimicking GBS without any systemic manifestation of arsenic intoxication.
CONCLUSIONS
The present case study emphasizes the need to consider arsenic intoxication in patients presenting with acute demyelinating neuropathies and histories of herbal medication use.
目的
我们报告了一例以孤立性多发性神经病表现、类似于格林-巴利综合征（GBS）的病例，该患者与砷暴露有关。
病例
一名 43 岁男性因进行性四肢瘫痪 5 天前来我院急诊就诊。他的临床病程和实验室数据均符合 GBS 的典型表现。然而，由于他最近使用了草药药物，我们对几种重金属的存在进行了筛查。尿无机砷浓度的连续分析证实存在砷暴露。他被诊断为砷中毒性多发性神经病，类似于 GBS，而无任何砷中毒的全身表现。
结论
本病例研究强调，对于出现急性脱髓鞘性神经病和草药药物使用史的患者，需要考虑砷中毒。
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