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日本野生啮齿动物中的新型鼠诺如病毒样基因。

Novel murine norovirus-like genes in wild rodents in Japan.

作者信息

Tsunesumi Naoto, Sato Go, Iwasa Masahiro, Kabeya Hidenori, Maruyama Soichi, Tohya Yukinobu

机构信息

Laboratory of Veterinary Microbiology, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan.

出版信息

J Vet Med Sci. 2012 Sep;74(9):1221-4. doi: 10.1292/jvms.12-0106. Epub 2012 May 16.

Abstract

Novel murine norovirus (MNV)-like sequences were detected in 7 (14.9%) of 47 fecal and intestinal samples obtained from wild rodents in Japan. Sequencing and genetic analyses of the 7 MNV-like genes, 6 derived from Apodemus speciosus and 1 from Rattus rattus, suggested that these sequences form a cluster distinct from known MNV within genogroup V and differed even among clusters of wild rodents. Considering these results, MNV might be genetically diverse depending on the host species or distribution. This is the first report suggesting the prevalence of MNV in A. speciosus and R. rattus.

摘要

在从日本野生啮齿动物采集的47份粪便和肠道样本中,有7份(14.9%)检测到了新型鼠诺如病毒(MNV)样序列。对这7个MNV样基因进行测序和遗传分析,其中6个来自日本姬鼠,1个来自黑家鼠,结果表明这些序列在基因组V中形成了一个与已知MNV不同的簇,甚至在野生啮齿动物的簇之间也存在差异。考虑到这些结果,MNV可能因宿主物种或分布不同而具有遗传多样性。这是首次报道提示MNV在日本姬鼠和黑家鼠中的流行情况。

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