Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Japan.
Angew Chem Int Ed Engl. 2012 Jul 9;51(28):7007-10. doi: 10.1002/anie.201203005. Epub 2012 Jun 4.
Easy access: a strontium/Schiff base complex as catalyst for the title reaction provided straightforward access to enantiomerically enriched spiro[imidazolidine-4,3'-oxindole] compounds, as well as a spiro[imidazoline-4,3'-oxindole] through a two-step conversion from the Mannich adduct.
作为催化剂的锶/Schiff 碱配合物为标题反应提供了直接通向对映体富集的螺[咪唑烷-4,3'-吲哚]化合物的途径,以及通过曼尼希加成物的两步转化得到的螺[咪唑啉-4,3'-吲哚]。