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Positron emission tomography imaging for the assessment of mild traumatic brain injury and chronic traumatic encephalopathy: recent advances in radiotracers.用于评估轻度创伤性脑损伤和慢性创伤性脑病的正电子发射断层扫描成像：放射性示踪剂的最新进展
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本文引用的文献

1
Dreaming and offline memory processing.做梦与离线记忆处理。
Curr Biol. 2010 Dec 7;20(23):R1010-3. doi: 10.1016/j.cub.2010.10.045.
2
The cognitive neuroscience of sleep: neuronal systems, consciousness and learning.睡眠的认知神经科学：神经元系统、意识与学习
Nat Rev Neurosci. 2002 Sep;3(9):679-93. doi: 10.1038/nrn915.
3
Dreaming and REM sleep are controlled by different brain mechanisms.做梦和快速眼动睡眠受不同的大脑机制控制。
Behav Brain Sci. 2000 Dec;23(6):843-50; discussion 904-1121. doi: 10.1017/s0140525x00003988.
4
Sleep and dreaming disturbances in closed head injury patients.闭合性颅脑损伤患者的睡眠与梦境障碍
J Neurol Neurosurg Psychiatry. 1982 Jan;45(1):78-80. doi: 10.1136/jnnp.45.1.78.
5
Dreams of subjects with loss of memory for recent events.近期事件记忆丧失患者的梦境。
Psychophysiology. 1969 Nov;6(3):358-65. doi: 10.1111/j.1469-8986.1969.tb02913.x.

脑损伤导致的记忆缺陷：独特的PET发现与梦境改变。

Memory deficits due to brain injury: unique PET findings and dream alterations.

作者信息

Nishida Masaki, Nariai Tadashi, Hiura Mikio, Ishii Kenji, Nishikawa Toru

机构信息

Section of Psychiatry and Behavioral Science, Tokyo Medical and Dental University Graduate School, Bunkyo, Japan.

出版信息

BMJ Case Rep. 2011 Dec 1;2011:bcr0920114845. doi: 10.1136/bcr.09.2011.4845.

DOI:10.1136/bcr.09.2011.4845
PMID:22674950
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3229401/
Abstract

The authors herein report the case of a young male with memory deficits due to a traumatic head injury, who presented with sleep-related symptoms such as hypersomnia and dream alterations. Although MRI and polysomnography showed no abnormalities, (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) and (11)C flumazenil (FMZ)-PET revealed findings consistent with cerebral damage to the affected temporal region. The memory deficit of the patient gradually improved in parallel with the relief of the sleep-related symptoms. FDG-PET showed considerable improvement in glucose metabolism when he had recovered, however, evidence of neural loss remained in the FMZ-PET findings.

摘要

本文作者报告了一例因创伤性脑损伤导致记忆缺陷的年轻男性病例，该患者出现了与睡眠相关的症状，如嗜睡和梦境改变。尽管磁共振成像（MRI）和多导睡眠图检查未发现异常，但氟代脱氧葡萄糖正电子发射断层扫描（FDG-PET）和碳-11氟马西尼（FMZ）-PET显示出与患侧颞叶脑损伤相符的结果。患者的记忆缺陷随着与睡眠相关症状的缓解而逐渐改善。当他康复时，FDG-PET显示葡萄糖代谢有显著改善，然而，FMZ-PET检查结果仍显示存在神经损失的迹象。