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纤维蛋白胶作为辅助悬带手术的效果。

Effect of fibrin glue as an adjuvant to hang-back surgery.

机构信息

Department of Ophthalmology, Kim’s Eye Hospital, Konyang University College of Medicine, Seoul, South Korea.

出版信息

BMC Ophthalmol. 2012 Jun 7;12:14. doi: 10.1186/1471-2415-12-14.

DOI:10.1186/1471-2415-12-14
PMID:22677044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3473302/
Abstract

BACKGROUND

The hang-back surgery is a useful technique in the field of strabismus surgery. The aim of this study is to determine the stabilizing effects of fibrin glue as an adjuvant to hang-back surgery.

MATERIALS AND METHODS

Four (4)-mm hang-back recessions of the superior rectus muscle was performed in 32 eyes of 16 rabbits. Only in the left eye of the 16 rabbits, fibrin glue was applied between the recessed muscle bed and the sclera at the end of hang-back surgery (fibrin glue group). After 6 weeks, we compared the stability of the recessed rectus muscle between the fibrin glue group and the control group by evaluating the displacement of the muscle.

RESULTS

The frequency of stable insertion of the recessed muscle at the intended site was greater in the fibrin glue group (9 eyes) compared to the control group (3 eyes) (p=0.028). In the control group, 5 eyes showed anterior displacement and 8 eyes showed posterior displacement and in the fibrin glue group, 1 eye showed anterior displacement, and 6 eyes showed posterior displacement. Anterior displacement was more common in the control group (6.3% Vs 31.3%). The control group and the fibrin glue group showed similar histological findings on microscopic examination.

CONCLUSIONS

Fibrin glue is effective in stabilizing the new rectus muscle insertion and decreasing the displacement in the hang-back surgery.

摘要

背景

后退手术是斜视手术领域的一种有用技术。本研究旨在确定纤维蛋白胶作为后退手术辅助手段的稳定效果。

材料和方法

在 16 只兔子的 32 只眼睛中进行了 4 毫米的上直肌后退。在这 16 只兔子中,只有左眼在后退手术结束时在后退肌肉床和巩膜之间应用纤维蛋白胶(纤维蛋白胶组)。6 周后,通过评估肌肉移位,比较纤维蛋白胶组和对照组后退直肌的稳定性。

结果

纤维蛋白胶组(9 只眼)稳定插入预期部位的频率高于对照组(3 只眼)(p=0.028)。在对照组中,5 只眼出现前移位,8 只眼出现后移位,而在纤维蛋白胶组中,1 只眼出现前移位,6 只眼出现后移位。对照组(6.3%比 31.3%)更常见前移位。对照组和纤维蛋白胶组在显微镜检查下的组织学发现相似。

结论

纤维蛋白胶在稳定新直肌插入和减少后退手术中的移位方面是有效的。

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本文引用的文献

1
A new modfied anchored suspension-recession (so-called "hang-back" technique for high risk strabismus surgery.一种新的改良锚定悬吊后徙术(即用于高风险斜视手术的所谓“回退”技术)。
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A comparison of hang-back with conventional recession surgery for exotropia.外斜视的“退缩”术与传统后退手术的比较。
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Long-term results of hang-back lateral rectus recession.后徙式外直肌后退术的长期效果
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Adal-1 bioadhesive for sutureless recession muscle surgery: a clinical trial.用于无缝合退缩肌手术的Adal-1生物黏附剂:一项临床试验。
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Bimedial hang-back recession -- outcomes and surgical response.双内侧后徙术——手术效果及反应
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Tissue adhesives for a sutureless fadenoperation: an experimental study in a rabbit model.用于无缝线埋线手术的组织粘合剂:在兔模型中的实验研究
Invest Ophthalmol Vis Sci. 2004 Dec;45(12):4340-5. doi: 10.1167/iovs.04-0049.
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Comparison of hang-back and conventional recession surgery for horizontal strabismus.水平斜视的后徙悬吊术与传统后徙术的比较。
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Evaluation of application techniques of fibrin sealant to prevent cerebrospinal fluid leakage: a new device for the application of aerosolized fibrin glue.评估纤维蛋白密封剂预防脑脊液漏的应用技术:一种用于雾化纤维蛋白胶应用的新装置。
Neurosurgery. 1999 Feb;44(2):332-7. doi: 10.1097/00006123-199902000-00048.
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Effect of fibrin glue in the reduction of postthoracotomy alveolar air leak.纤维蛋白胶在减少开胸术后肺泡漏气中的作用。
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