Tarasova I V, Vol'f N V, Trubnikova O A, Barbarash O L
Zh Nevrol Psikhiatr Im S S Korsakova. 2012;112(3 Pt 1):13-7.
We studied the changes of electroencephalograms (EEG) related to on-pump coronary artery bypass grafting (CABG) in 28 right-handed male patients with coronary heart disease (CHD), 10 from which had accompanying moderated (30-50%) carotid artery (CA) stenoses. All EEG studies were performed 3-5 days before and 7-11 days after CABG. EEG data of healthy age-matched males (n=14) were examined. Before surgery, the CHD patients differed from the control group by less expressed theta2 and beta1 rhythm power asymmetry. The differences demonstrated worse conditions for cognitive processes in CHD patients. After CABG, the higher power of teta1 and 2 rhythms, predominantly in the frontal lobe of the left hemisphere which was mostly expressed in patients with CA stenosis, was observed in all CHD patients. This effect can be considered as the appearance of ischemic neuronal injury caused by on-pump CABG. The localization of changes in the frontal cortex of the left hemisphere can be related to a high vulnerability of these regions. The deficit of cerebral blood flow in these regions will define a clinical picture of cognitive decline after CABG.
我们研究了28例患有冠心病（CHD）的右利手男性患者在体外循环冠状动脉旁路移植术（CABG）期间脑电图（EEG）的变化，其中10例伴有中度（30 - 50%）颈动脉（CA）狭窄。所有EEG研究均在CABG术前3 - 5天和术后7 - 11天进行。对年龄匹配的健康男性（n = 14）的EEG数据进行了检查。术前，CHD患者与对照组的区别在于θ2和β1节律功率不对称表达较少。这些差异表明CHD患者的认知过程状况较差。CABG术后，在所有CHD患者中均观察到θ1和θ2节律功率升高，主要出现在左半球额叶，在伴有CA狭窄的患者中表现最为明显。这种效应可被视为体外循环CABG导致的缺血性神经元损伤的出现。左半球额叶变化的定位可能与这些区域的高易损性有关。这些区域的脑血流量不足将决定CABG术后认知功能下降的临床表现。
