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维生素 D 的新参考值。

New reference values for vitamin D.

出版信息

Ann Nutr Metab. 2012;60(4):241-6. doi: 10.1159/000337547. Epub 2012 Jun 1.

DOI:10.1159/000337547
PMID:22677925
Abstract

In the recent past, many studies have been published on the association between vitamin D and bone health or the risk of various chronic diseases. Thus, the D-A-CH reference values [D-A-CH arises from the initial letters of the common country identification for the countries Germany (D), Austria (A) and Switzerland (CH)] for the intake of vitamin D have been revised based on a critical review by the German Nutrition Society. Both dietary intake and endogenous synthesis contribute to the body's vitamin D status. Since different factors modulate the extent of endogenous vitamin D formation, quantification is hardly possible. Therefore, the new reference values for vitamin D intake are specified for a situation in which endogenous synthesis is completely missing. Based on the findings of the critical review, serum 25-hydroxyvitamin D concentrations of 50 nmol/l or higher are considered an indicator of an optimal vitamin D status. When endogenous synthesis is missing, adequate vitamin D intake is estimated as 20 µg per day for children, adolescents and adults. Dietary vitamin D intake from habitual diet is not sufficient to achieve this value. This gap has to be covered by endogenous vitamin D synthesis and/or additional intake of vitamin D. It is clearly stated that the desired vitamin D supply can be achieved without using vitamin D supplements by frequent sun exposure.

摘要

在最近的过去,已经有许多研究发表了关于维生素 D 与骨骼健康或各种慢性疾病风险之间的关系。因此,德国营养学会(German Nutrition Society)对其进行了严格审查,对 D-A-CH(D-A-CH 源于德国(D)、奥地利(A)和瑞士(CH)这三个国家的国家识别首字母)的维生素 D 摄入量参考值进行了修订。饮食摄入和内源性合成都有助于人体的维生素 D 状态。由于不同的因素会调节内源性维生素 D 形成的程度,因此很难对其进行量化。因此,新的维生素 D 摄入量参考值是针对完全缺乏内源性合成的情况指定的。基于严格审查的结果,血清 25-羟维生素 D 浓度达到或高于 50 nmol/L 被认为是维生素 D 状态最佳的指标。当内源性合成缺失时,儿童、青少年和成人每天估计需要摄入 20 微克的维生素 D 才能达到这一水平。从习惯性饮食中摄入的膳食维生素 D 不足以达到这一数值。该报告明确指出,通过经常晒太阳,无需使用维生素 D 补充剂就可以实现所需的维生素 D 供应。

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