Kosinets V A, Osochuk S S, Iarotskaia N N
Khirurgiia (Mosk). 2012(2):60-3.
The experiment has been carried out on 55 male rabbits of chinchilla breed. For the first time in comparative aspect influence of preparations "Citoflavin" and "Neoton" on a phospholipid spectrum of liver mitochondrial membranes is studied at an experimental widespread purulent peritonitis. It is established that in the postoperative period "Citoflavin", which contains amber acid, influences on phospholipid structure of mitochondria of animals with a widespread purulent peritonitis by percentage decrease of lisophosphatides, level increase of polyglycerophosphatide and cardiolipin more effectively.
该实验在55只雄性青紫蓝兔身上进行。首次在比较层面研究了制剂“细胞黄素”和“新托宁”对实验性广泛性化脓性腹膜炎时肝线粒体膜磷脂谱的影响。结果表明,在术后时期,含有琥珀酸的“细胞黄素”通过降低溶血磷脂百分比、提高聚甘油磷脂和心磷脂水平,更有效地影响患有广泛性化脓性腹膜炎动物线粒体的磷脂结构。