McKee P H, Fletcher C D, Rasbridge S A
Department of Histopathology, St. Thomas's Hospital Medical School, London, England.
Am J Dermatopathol. 1990 Dec;12(6):552-61. doi: 10.1097/00000372-199012000-00004.
Eccrine epithelioma is an exceedingly rare cutaneous tumor thought to represent the malignant counterpart of the eccrine dermal syringoma. To data, only 10 accepted cases appear to have been reported. Two additional cases are described here and the literature is reviewed. The first case showed the typical histologic features of eccrine epithelioma. The second case showed extensive clear cell change (due to glycogen accumulation), reminiscent of the clear cell syringoma; conspicuous pseudo-apocrine metaplasia was also noted. The latter appearance has not been previously described in eccrine epithelioma.
小汗腺上皮瘤是一种极为罕见的皮肤肿瘤,被认为是小汗腺真皮导管瘤的恶性对应物。到目前为止,似乎仅有10例公认的病例被报道。本文描述了另外2例病例并对文献进行了综述。第一例显示了小汗腺上皮瘤典型的组织学特征。第二例显示出广泛的透明细胞改变(由于糖原积聚),使人联想到透明细胞汗腺导管瘤;还注意到明显的假顶浆分泌化生。后一种表现以前在小汗腺上皮瘤中未曾描述过。