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静水椎实螺神经损伤后神经系统连接的重新形成。

The re-formation of connections in the nervous sytem of Lymnaea stagnalis after nerve injury.

作者信息

Janse C, Kits K S, Lever A J

出版信息

Malacologia. 1979;18(1-2):485-8.

PMID:226810
Abstract

Changes in the tentacle reflex pathway of the pond snail Lymnaea stagnalis induced by peripheral nerve injury were studied with behavioural and electrophysiological techniques. After nerve injury regeneration of sensory axons is obtained in 6-12 days, suggesting an axonal outgrowth at a rate of 1 mm per day. Recovery of the tentacle reflex takes much more time indicating that synaptic efficacy is affected considerably by the period of sensory deprivation following nerve injury.

摘要

运用行为学和电生理学技术,研究了外周神经损伤诱导的静水椎实螺触手反射通路的变化。神经损伤后,感觉轴突在6 - 12天内实现再生,这表明轴突以每天1毫米的速度生长。触手反射的恢复需要更多时间,这表明神经损伤后感觉剥夺期对突触效能有显著影响。

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引用本文的文献

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Identification of the role of C/EBP in neurite regeneration following microarray analysis of a L. stagnalis CNS injury model.通过对沼虾中枢神经系统损伤模型的基因芯片分析鉴定 C/EBP 在神经突再生中的作用。
BMC Neurosci. 2012 Jan 4;13:2. doi: 10.1186/1471-2202-13-2.
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Lymnaea epidermal growth factor promotes axonal regeneration in CNS organ culture.椎实螺表皮生长因子促进中枢神经系统器官培养中的轴突再生。
J Neurosci. 2001 Dec 1;21(23):9345-54. doi: 10.1523/JNEUROSCI.21-23-09345.2001.