Schmidt C A, Wood M N, Gan K A, Razzouk A J
Department of Surgery, Loma Linda University, California 92354.
Am Surg. 1990 Dec;56(12):745-8.
From July 1985 to July 1989, Loma Linda University Medical Center evaluated 46 thoracoabdominal aortic aneurysms (TAAAs). Forty patients were taken to surgery--18 (45%) were operated on an emergency basis for reasons including rupture (12 patients, 30%), dissection (5 patients, 12.5%), and severe pain (1 patient). The overall mortality for all operated patients was five (12.5%-17% for emergency surgery versus 9% for elective surgery). Nonfatal complications occurred in 40 per cent of patients (16). The overall incidence of paraplegia was 10 per cent (4/40), emergency patients 17 per cent (3/18) versus elective patients 4.5 per cent (1/22). Careful preoperative evaluation, standardization of operative technique, and good postoperative management have improved the outlook for these patients who otherwise would progress to eventual rupture and death. Because mortality and morbidity are substantially reduced in elective patients, we recommend that all patients with TAAAs be evaluated for surgery as soon as diagnosis is made.
1985年7月至1989年7月期间,洛马林达大学医学中心对46例胸腹主动脉瘤(TAAA)患者进行了评估。40例患者接受了手术——18例(45%)因包括破裂(12例患者,30%)、夹层(5例患者,12.5%)和剧痛(1例患者)等原因而接受急诊手术。所有接受手术患者的总体死亡率为5例(急诊手术为12.5% - 17%,择期手术为9%)。40%的患者发生了非致命性并发症(16例)。截瘫的总体发生率为10%(4/40),急诊患者为17%(3/18),而择期患者为4.5%(1/22)。仔细的术前评估、手术技术的标准化以及良好的术后管理改善了这些患者的预后,否则他们最终会发展为破裂和死亡。由于择期手术患者的死亡率和发病率大幅降低,我们建议一旦确诊,所有TAAA患者都应尽快接受手术评估。