Charring Cross Hospital, Orthopaedic Department, London, UK.
J Orthop Surg Res. 2012 Jun 8;7:24. doi: 10.1186/1749-799X-7-24.
BACKGROUND: Pulsed electromagnetic fields (PEMF) stimulation for the treatment of bone nonunion or delayed union have been in use for several years, but on a limited basis. The aim of this study was to assess the overall efficacy of the method in tibial delayed unions and nonunions and identify factors that could affect the final outcome. METHODS: We prospectively reviewed 44 patients (27 men) with a mean age of 49.6 ± 18.4 years that received PEMF therapy due to tibial shaft delayed union or nonunion. In all cases, fracture gap was less than 1 cm and infection or soft tissue defects were absent. RESULTS: Fracture union was confirmed in 34 cases (77.3%). No relationship was found between union rate and age (p = 0.819), fracture side (left or right) (p = 0.734), fracture type (simple or comminuted, open or closed) (p = 0.111), smoking (p = 0.245), diabetes (p = 0.68) and initial treatment method applied (plates, nail, plaster of paris) (p = 0.395). The time of treatment onset didn't affect the incidence of fracture healing (p = 0.841). Although statistical significance was not demonstrated, longer treatment duration showed a trend of increased probability of union (p = 0.081). CONCLUSION: PEMF stimulation is an effective non-invasive method for addressing non-infected tibial union abnormalities. Its success is not associated with specific fracture or patient related variables and it couldn't be clearly considered a time-dependent phenomenon.
背景:脉冲电磁场(PEMF)刺激已应用于治疗骨不连或延迟愈合多年,但应用范围有限。本研究旨在评估该方法治疗胫骨延迟愈合和不愈合的总体疗效,并确定可能影响最终结果的因素。
方法:我们前瞻性地回顾了 44 例(27 例男性)平均年龄为 49.6±18.4 岁的患者,这些患者因胫骨骨干延迟愈合或不愈合而接受 PEMF 治疗。在所有病例中,骨折间隙均小于 1cm,且无感染或软组织缺损。
结果:34 例(77.3%)骨折愈合。愈合率与年龄(p=0.819)、骨折侧(左侧或右侧)(p=0.734)、骨折类型(简单或粉碎性、开放性或闭合性)(p=0.111)、吸烟(p=0.245)、糖尿病(p=0.68)以及初始应用的治疗方法(钢板、钉、石膏)(p=0.395)无关。治疗开始时间不影响骨折愈合的发生率(p=0.841)。虽然未显示统计学意义,但较长的治疗持续时间显示出愈合概率增加的趋势(p=0.081)。
结论:PEMF 刺激是治疗非感染性胫骨愈合异常的一种有效非侵入性方法。其疗效与特定的骨折或患者相关因素无关,也不能明确地被认为是一个时间依赖性现象。
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