骨折愈合的电刺激疗法科学。
The science of electrical stimulation therapy for fracture healing.
作者信息
Kuzyk Paul Rt, Schemitsch Emil H
机构信息
Department of Surgery, University of Toronto, Toronto, ON, Canada.
出版信息
Indian J Orthop. 2009 Apr;43(2):127-31. doi: 10.4103/0019-5413.50846.
Abstract
This article is a brief review of the basic science research conducted in the field of electrical stimulation for fracture healing. Direct electrical current, capacitive coupling, and inductive coupling have been studied as potential techniques to enhance fracture healing through the proliferation and differentiation of osteogenic cells. These techniques are particularly appealing as they offer a potential minimally invasive solution to the difficult clinical problem of delayed fracture healing and nonunion. Basic science studies have shown conclusively that electrical stimulation techniques lead to bone cell proliferation and have attempted to elucidate the intracellular processes by which this bone cell proliferation occurs. Further basic science and clinical research is required to enhance the effectiveness of this therapy for the treatment of fracture nonunions.
摘要
本文是对电刺激促进骨折愈合领域基础科学研究的简要综述。直流电、电容耦合和电感耦合已作为潜在技术进行研究，旨在通过成骨细胞的增殖和分化来促进骨折愈合。这些技术特别有吸引力，因为它们为解决骨折延迟愈合和骨不连这一棘手的临床问题提供了一种潜在的微创解决方案。基础科学研究已确凿表明，电刺激技术可导致骨细胞增殖，并试图阐明这种骨细胞增殖发生的细胞内过程。需要进一步开展基础科学和临床研究，以提高这种疗法治疗骨折不连的有效性。
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