Payen J-F, Isnardon S, Lavolaine J, Bouzat P, Vinclair M, Francony G
Pôle d'anesthésie-réanimation, hôpital Albert-Michallon, BP 217, 38043 Grenoble cedex 09, France.
Ann Fr Anesth Reanim. 2012 Jun;31(6):e155-9. doi: 10.1016/j.annfar.2012.04.020. Epub 2012 Jun 6.
Pupil size reflects the balance between sympathetic and parasympathetic systems. Due to technological advances, accurate and repeated pupil size measurements are possible using infrared, video-recorded pupillometers. Two pupil size reflexes are assessed: the pupillary reflex dilation during noxious stimulation, and the pupil light reflex when the pupil is exposed to the light. The pupillary reflex dilation estimates the level of analgesia in response to a painful procedure or to a calibrated noxious stimulus, i.e., tetanic stimulus, in nonverbal patients. This might be of particular interest in optimizing the management of opioids in anaesthetized patients and in assessing pain levels in the intensive care unit. The pupil light reflex measurement is part of the routine monitoring for severely head-injured patients. The impact of pupillometry in this condition remains to be determined.
瞳孔大小反映了交感神经系统和副交感神经系统之间的平衡。由于技术进步,使用红外视频记录瞳孔测量仪可以进行准确且重复的瞳孔大小测量。评估两种瞳孔大小反射:有害刺激期间的瞳孔反射性扩张,以及瞳孔暴露于光线时的瞳孔对光反射。瞳孔反射性扩张可估计非语言患者对疼痛程序或校准的有害刺激(即强直刺激)的镇痛水平。这对于优化麻醉患者的阿片类药物管理以及评估重症监护病房中的疼痛水平可能特别有意义。瞳孔对光反射测量是重度颅脑损伤患者常规监测的一部分。瞳孔测量在此种情况下的影响仍有待确定。