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[人类新皮质运动区的胆碱能锥体神经元]

[Cholinergic pyramidal neurons of the motor region of human neocortex].

作者信息

Motavkin P A, Okhotin V E, Sulimov G Iu

出版信息

Arkh Anat Gistol Embriol. 1990 Aug;99(8):34-9.

PMID:2268188
Abstract

By means of histochemical methods for revealing +choline acetyltransferase (ChAT) and acetylcholinesterase (AChE) cytoarchitectonic of the field 4 of the motor cortex of the cerebrum has been studied in 5 persons at the age of 33-65 years. An essential part of neurons at revealing AChE and most of them at revealing ChAT do not react. Among giant pyramidal neurons (Bets) according to ChAT activity, 4 types are distinguished: neurons with low, middle, high and very high activity. The presence of ChAT is ascertained in middle and large pyramidal neurons of the III layer. Presence of ChAT-positive synapses is demonstrated in apical dendrites. A conclusion is made that less part of the pyramidal in the III, V layers are cholinergic ones.

摘要

通过组织化学方法显示大脑运动皮层4区的胆碱乙酰转移酶(ChAT)和乙酰胆碱酯酶(AChE)细胞结构,对5名年龄在33至65岁的人进行了研究。在显示AChE时,大部分神经元无反应,显示ChAT时,大部分神经元也无反应。根据ChAT活性,在巨大锥体细胞(贝茨细胞)中可区分出4种类型:低活性、中等活性、高活性和非常高活性的神经元。在第III层的中型和大型锥体细胞中确定有ChAT存在。在顶端树突中显示有ChAT阳性突触。得出的结论是,第III、V层中锥体细胞的胆碱能细胞较少。

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[Cholinergic pyramidal Betz's and Meynert's neurons in human cerebral cortex].
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