Department of Medicine, Division of Hematology/Oncology, University of North Carolina at Chapel Hill, NC, USA.
Thromb Res. 2012 Apr;129 Suppl 1:S66-8. doi: 10.1016/S0049-3848(12)70019-1.
Acquired hemophilia is a rare but potentially morbid complication in patients with cancer. It may be seen in patients with hematologic neoplasms (usually lymphoproliferative disorders) or with solid tumors. Although the presence of an underlying malignancy portends a worse outcome, the literature suggests that the usual principles of treatment, including immunosuppression, apply to these patients. However, appropriate consideration should be given to the choice of agents, depending on individual risk factors for complications such as thrombosis and infection.
获得性血友病是癌症患者中一种罕见但潜在致命的并发症。它可能发生在血液系统恶性肿瘤（通常为淋巴增生性疾病）或实体瘤患者中。尽管潜在恶性肿瘤的存在预示着预后更差，但文献表明，包括免疫抑制在内的常规治疗原则适用于这些患者。然而，应根据个体发生血栓形成和感染等并发症的风险因素，适当考虑药物选择。
