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中国人群痴呆及主要亚型的患病率:1980-2010 年痴呆患病率调查的荟萃分析。

Prevalence of dementia and major dementia subtypes in the Chinese populations: a meta-analysis of dementia prevalence surveys, 1980-2010.

机构信息

School of Radiation Medicine and Public Health, Soochow University, 199 Ren ai Road, Suzhou Industrial Park, Suzhou 215123, Jiangsu, China.

出版信息

J Clin Neurosci. 2012 Oct;19(10):1333-7. doi: 10.1016/j.jocn.2012.01.029. Epub 2012 Jun 8.

DOI:10.1016/j.jocn.2012.01.029
PMID:22682650
Abstract

The aim of this study was to determine the prevalence of dementia and its major subtypes in China. Forty-eight eligible studies were included in this review. The pooled prevalence for the population aged 60 years and older of Alzheimer's disease (AD) was 1.9%, vascular dementia (VaD) was 0.9%, and total dementia was 3.0%. The prevalence of VaD was significantly higher in Northern China than in Southern China. The prevalence of VaD was significantly higher in urban compared to rural areas. The prevalence of dementia and prevalence of AD increased with age in both males and females, and a higher prevalence of AD than VaD was observed in all age groups. AD has become more common than VaD in China since 1990. The current prevalence of dementia in China may be similar to that of developed countries.

摘要

本研究旨在确定中国痴呆症及其主要亚型的患病率。本综述纳入了 48 项符合条件的研究。60 岁及以上人群阿尔茨海默病(AD)的患病率为 1.9%,血管性痴呆(VaD)为 0.9%,总痴呆症为 3.0%。北方人群 VaD 的患病率明显高于南方人群。与农村地区相比,城市人群 VaD 的患病率明显更高。男性和女性的痴呆症和 AD 患病率均随年龄增长而增加,且在所有年龄组中 AD 的患病率均高于 VaD。自 1990 年以来,AD 在我国比 VaD 更为常见。目前我国痴呆症的患病率可能与发达国家相似。

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