替代补体途径中豚鼠B因子的天冬酰胺连接寡糖的结构

Structures of the asparagine-linked oligosaccharides of guinea-pig factor B of the alternative complement pathway.

作者信息

Mizuochi T, Hamako J, Titani K, Matsushita M, Okada H

机构信息

Institute for Comprehensive Medical Science, Fujita Health University School of Medicine, Aichi, Japan.

出版信息

Biochem J. 1990 Dec 1;272(2):533-5. doi: 10.1042/bj2720533.

DOI:10.1042/bj2720533

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1149734/

Abstract

This paper describes the structures of the asparagine-linked oligosaccharides of two forms of guinea-pig Factor B of the alternative complement pathway with different Mr values. Oligosaccharides were quantitatively liberated from both glycoproteins by hydrazinolysis, fractionated by paper electrophoresis and Bio-Gel P-4 column chromatography, and their structures determined by sequential exoglycosidase digestions in conjunction with methylation analysis. Both glycoproteins were shown to have the same biantennary complex-type oligosaccharides but it is suggested that they contain different numbers of oligosaccharide chains.

摘要

本文描述了替代补体途径中两种不同分子量的豚鼠B因子的天冬酰胺连接寡糖的结构。通过肼解从两种糖蛋白中定量释放寡糖，经纸电泳和生物凝胶P-4柱色谱法分级分离，并结合甲基化分析通过顺序外切糖苷酶消化确定其结构。结果表明，两种糖蛋白具有相同的双触角复合型寡糖，但推测它们含有的寡糖链数量不同。

相似文献

1

Structures of the asparagine-linked oligosaccharides of guinea-pig factor B of the alternative complement pathway.替代补体途径中豚鼠B因子的天冬酰胺连接寡糖的结构

Biochem J. 1990 Dec 1;272(2):533-5. doi: 10.1042/bj2720533.

2

Structures of the asparagine-linked oligosaccharide chains of human von Willebrand factor. Occurrence of blood group A, B, and H(O) structures.人血管性血友病因子天冬酰胺连接的寡糖链结构。血型A、B和H（O）结构的存在情况。

J Biol Chem. 1992 May 5;267(13):8723-31.

3

Molecular characterization of Limulus polyphemus C-reactive protein. II. Asparagine-linked oligosaccharides.鲎C反应蛋白的分子特征。II. 天冬酰胺连接的寡糖。

Eur J Biochem. 1993 May 15;214(1):99-110. doi: 10.1111/j.1432-1033.1993.tb17901.x.

4

Structural studies of the asparagine-linked sugar chains of two immunoglobulin M's purified from a patient with Waldenström's macroglobulinemia.

Arch Biochem Biophys. 1989 Mar;269(2):463-75. doi: 10.1016/0003-9861(89)90130-6.

5

Structures of the sugar chains of mouse immunoglobulin G.小鼠免疫球蛋白G糖链的结构

Arch Biochem Biophys. 1987 Sep;257(2):387-94. doi: 10.1016/0003-9861(87)90581-9.

6

Asparagine-linked sugar chains of glycoproteins in calf thymocyte plasma membrane. Isolation and fractionation of oligosaccharides liberated by hydrazinolysis.小牛胸腺细胞质膜中糖蛋白的天冬酰胺连接糖链。肼解释放的寡糖的分离与分级分离。

J Biochem. 1980 Jul;88(1):241-6.

7

Subcomponents C1q of the first component of guinea pig and mouse complement. Comparative study of their asparagine-linked sugar chains.豚鼠和小鼠补体第一成分的亚组分C1q。其天冬酰胺连接糖链的比较研究。

Biochim Biophys Acta. 1983 Mar 15;756(1):28-35. doi: 10.1016/0304-4165(83)90020-x.

8

Structures of the sugar chains of rabbit immunoglobulin G: occurrence of asparagine-linked sugar chains in Fab fragment.兔免疫球蛋白G糖链的结构：Fab片段中存在天冬酰胺连接的糖链。

Biochemistry. 1985 Sep 24;24(20):5551-7. doi: 10.1021/bi00341a040.

9

The structures of the asparagine-linked sugar chains of human apolipoprotein B-100.人载脂蛋白B - 100的天冬酰胺连接糖链结构

Arch Biochem Biophys. 1989 Aug 15;273(1):197-205. doi: 10.1016/0003-9861(89)90179-3.

10

Carbohydrate structures of human interleukin 5 expressed in Chinese hamster ovary cells.

J Biochem. 1991 Nov;110(5):693-701. doi: 10.1093/oxfordjournals.jbchem.a123643.

本文引用的文献

1

Studies on the structures of the carbohydrate moiety of human prothrombin.

J Biochem. 1981 Oct;90(4):1023-31. doi: 10.1093/oxfordjournals.jbchem.a133554.

2

Substrate specificity of Diplococcal beta-N-acetylhexosaminidase, a useful enzyme for the structural studies of complex type asparagine-linked sugar chains.双球菌β-N-乙酰己糖胺酶的底物特异性，一种对复杂型天冬酰胺连接糖链结构研究有用的酶。

Biochem Biophys Res Commun. 1981 May 15;100(1):226-32. doi: 10.1016/s0006-291x(81)80086-1.

3

Regulation of glycophorin of complement activation via the alternative pathway.通过替代途径对补体激活的血型糖蛋白的调节。

Biochem Biophys Res Commun. 1982 Sep 30;108(2):770-5. doi: 10.1016/0006-291x(82)90895-6.

4

Restriction of alternative complement pathway activation by sialosylglycolipids.唾液酸糖脂对替代补体途径激活的限制

Nature. 1982 Sep 16;299(5880):261-3. doi: 10.1038/299261a0.

5

Hydrazinolysis of asparagine-linked sugar chains to produce free oligosaccharides.天冬酰胺连接的糖链的肼解作用以产生游离寡糖。

Methods Enzymol. 1982;83:263-8. doi: 10.1016/0076-6879(82)83019-x.

6

Analysis of oligosaccharides by gel filtration.通过凝胶过滤法分析寡糖。

Methods Enzymol. 1982;83:105-26. doi: 10.1016/0076-6879(82)83008-5.

7

Structural and numerical variations of the carbohydrate moiety of immunoglobulin G.免疫球蛋白G碳水化合物部分的结构和数值变异

J Immunol. 1982 Nov;129(5):2016-20.

8

The structures of the carbohydrate moieties of bovine blood coagulation factor X.牛凝血因子X碳水化合物部分的结构

J Biol Chem. 1980 Apr 25;255(8):3526-31.

9

Structures of the sugar chains of mouse immunoglobulin G.小鼠免疫球蛋白G糖链的结构

Arch Biochem Biophys. 1987 Sep;257(2):387-94. doi: 10.1016/0003-9861(87)90581-9.

10

The C3 convertase of the alternative pathway of human complement. Enzymic properties of the bimolecular proteinase.人类补体替代途径的C3转化酶。双分子蛋白酶的酶学特性。

Biochem J. 1986 May 1;235(3):723-30. doi: 10.1042/bj2350723.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。