School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QJ, UK.
J Magn Reson. 2012 Jul;220:1-7. doi: 10.1016/j.jmr.2012.04.017. Epub 2012 May 8.
Chromatographic NMR describes the use of stationary phases or solvent additives, such as polymers, to modify the diffusion properties of analyte molecules and thereby improve the observed resolution in the diffusion domain. This paper demonstrates similar ideas using size exclusion chromatographic media and characterises the changes in the observed diffusion coefficient using a series of polymer molecular weight reference standards of known polydispersity. The results are interpreted in terms of a simple description of the size exclusion phenomena.
色谱核磁共振描述了使用固定相或溶剂添加剂（如聚合物）来改变分析物分子的扩散性质，从而提高扩散域中观察到的分辨率。本文使用尺寸排阻色谱介质展示了类似的想法，并使用一系列具有已知多分散性的聚合物分子量标准品来描述观察到的扩散系数的变化。结果根据简单的尺寸排阻现象描述进行了解释。
