Amodeo A, Di Donato R, Corno A, Mazzera E, Giannico S, Nava S, Marcelletti C
Department of Pediatric Cardiology and Cardiac Surgery, Ospedale Bambino Gesù, Rome, Italy.
Eur J Cardiothorac Surg. 1990;4(11):601-3; discussion 604. doi: 10.1016/1010-7940(90)90019-v.
The management of severe congenital mitral stenosis in infants and children is still controversial. We describe our experience with the use of a systemic atrioventricular (SAV) extracardiac conduit to bypass a hypoplastic systemic atrioventricular valve. An SAV extracardiac conduit has been used in six patients (left atrium--left ventricle in five, right atrium--right ventricle in one). One hospital death occurred due to mediastinitis and there were two late deaths, one due to progressive subaortic stenosis and one sudden, possibly due to arrhythmia. Postoperative cardiac catheterization performed in five patients showed reduction of the transmitral gradient from a mean of 16 mmHg to a mean of 5 mmHg. Calcification of the bioprosthetic valve occurred in two patients 3 1/2 years and 2 years respectively after the operation; one died from concomitant subaortic stenosis and one underwent conduit replacement. Although its long-term efficacy is limited, the SAV conduit seems the most reliable surgical option for infants and children with hypoplastic systemic atrioventricular valves unsuited to conventional surgery.
婴幼儿及儿童严重先天性二尖瓣狭窄的治疗仍存在争议。我们描述了使用体循环房室(SAV)心外管道绕过发育不全的体循环房室瓣的经验。6例患者使用了SAV心外管道(5例为左心房至左心室,1例为右心房至右心室)。1例患者因纵隔炎在医院死亡,2例患者出现晚期死亡,1例死于进行性主动脉瓣下狭窄,1例猝死,可能与心律失常有关。5例患者术后进行的心导管检查显示,二尖瓣跨瓣压差从平均16 mmHg降至平均5 mmHg。2例患者分别在术后3年半和2年出现生物瓣钙化;1例死于合并的主动脉瓣下狭窄,1例接受了管道置换。尽管其长期疗效有限,但对于不适合传统手术的发育不全的体循环房室瓣婴幼儿及儿童,SAV管道似乎是最可靠的手术选择。