Department of Anatomy, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.
Acta Histochem Cytochem. 2012 Apr 26;45(2):107-12. doi: 10.1267/ahc.10036. Epub 2012 Mar 10.
The objectives of this study were to investigate the time-course of influence of compression of bone tunnel wall in ligament reconstruction on tissue around the bone tunnel and to histologically examine the mechanism of preventing the complication of bone tunnel dilation, using rabbit tibia. A model in which the femoral origin of the extensor digitorum longus tendon was cut and inserted into a bone tunnel made proximal to the tibia was prepared in the bilateral hind legs of 20 Japanese white rabbits. In each animal, a tunnel was made using a drill only in the right leg, while an undersized bone tunnel was made by drilling and then dilated by compression using a dilator to the same tunnel size as that in the right leg. Animals were sacrificed at 0, 2, 4, 8 and 12 weeks after surgery (4 animals at each time point). Observation of bone tunnels by X-ray radiography showed osteosclerosis in the 2- and 4-week dilation groups. Osteosclerosis appeared as white lines around the bone tunnel on X-ray radiography. This suggests that dilation promotes callus formation in the bone tunnel wall and prevents the complication of bone tunnel enlargement after ligament reconstruction.
本研究旨在探讨重建韧带时骨隧道壁压缩对骨隧道周围组织的影响时间进程，并使用兔胫骨进行组织学检查，以防止骨隧道扩张并发症的发生机制。在 20 只日本白兔的双侧后腿中制备了一种模型，即将伸趾长肌的股骨起点切断并插入胫骨近端的骨隧道。在每只动物中，仅在右腿使用钻头制作隧道，而在左腿使用钻头制作小一号的隧道，然后使用扩张器扩张至与右腿相同的隧道大小。手术后 0、2、4、8 和 12 周（每个时间点 4 只动物）处死动物。X 射线射线照相观察骨隧道显示扩张 2 周和 4 周组出现骨硬化。骨硬化在 X 射线射线照相上表现为骨隧道周围的白线。这表明扩张促进了骨隧道壁中的骨痂形成，防止了韧带重建后骨隧道扩大的并发症。
