Hollsten D A, Katowitz J A
Department of Ophthalmology, Brooke Army Medical Center, Fort Sam Houston, Texas 78234.
Ophthalmic Plast Reconstr Surg. 1990;6(1):1-15. doi: 10.1097/00002341-199003000-00001.
The amniotic band syndrome is an unusual cause of craniofacial deformities. The syndrome, which is initiated by rupture of the amnion, results in an unpredictable combination of compression deformities of the fetus, construction or amputation defects of the extremities, and craniofacial clefting deformities. The type and extent of ophthalmic abnormalities are dependent on the band location and timing. They include a combination of bony orbital clefts or hypertelorism; lid anomalies such as colobomas, ptosis, and ectropion; lacrimal outflow obstruction; and globe involvement. We review the clinical course of 14 patients diagnosed with, or suspected as having, this syndrome and describe the methods of treatment. In most instances, multiple surgical procedures were required to restore function. Satisfactory cosmesis proved more difficult to obtain.
羊膜带综合征是导致颅面畸形的一种罕见病因。该综合征由羊膜破裂引发，会导致胎儿出现不可预测的一系列畸形组合，包括肢体受压畸形、肢体截断或缺失缺陷以及颅面裂畸形。眼部异常的类型和程度取决于羊膜带的位置和出现时间。这些异常包括眶骨裂或眼距过宽；眼睑异常，如睑裂缺损、上睑下垂和睑外翻；泪液引流阻塞；以及眼球受累。我们回顾了14例被诊断或疑似患有该综合征患者的临床病程，并描述了治疗方法。在大多数情况下，需要多次外科手术来恢复功能。而要获得令人满意的美容效果则更为困难。
