Department of Neuroendocrinology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
Gynecol Endocrinol. 2012 Dec;28(12):999-1001. doi: 10.3109/09513590.2012.692222. Epub 2012 Jun 12.
Autoimmune polyglandular syndromes are rare disorders characterized by failure of several endocrine glands, as well as non-endocrine organs, associated with immune-mediated tissue destruction. We report a rare case of polyglandular syndrome type II in a patient who presented with premature ovarian failure, Hashimoto's thyroiditis and empty sella associated with a diagnosis of differentiated thyroid carcinoma. This case probably represents the first report on this tumor in a patient with polyglandular disorder.
自身免疫性多腺体综合征是一种罕见的疾病,其特征是多个内分泌腺体以及非内分泌器官的功能衰竭,与免疫介导的组织破坏有关。我们报告了一例罕见的 II 型多腺体综合征病例,该患者表现为卵巢早衰、桥本甲状腺炎和空蝶鞍,同时伴有分化型甲状腺癌的诊断。本例可能是首例报道的多腺体疾病患者伴发此种肿瘤的病例。