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自身免疫性多腺体综合征:空蝶鞍、卵巢早衰、桥本甲状腺炎伴甲状腺癌的不常见表现。

Autoimmune polyglandular syndrome: an unusual presentation with empty sella, premature ovarian failure, and Hashimoto's thyroiditis associated with thyroid cancer.

机构信息

Department of Neuroendocrinology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.

出版信息

Gynecol Endocrinol. 2012 Dec;28(12):999-1001. doi: 10.3109/09513590.2012.692222. Epub 2012 Jun 12.

Abstract

Autoimmune polyglandular syndromes are rare disorders characterized by failure of several endocrine glands, as well as non-endocrine organs, associated with immune-mediated tissue destruction. We report a rare case of polyglandular syndrome type II in a patient who presented with premature ovarian failure, Hashimoto's thyroiditis and empty sella associated with a diagnosis of differentiated thyroid carcinoma. This case probably represents the first report on this tumor in a patient with polyglandular disorder.

摘要

自身免疫性多腺体综合征是一种罕见的疾病,其特征是多个内分泌腺体以及非内分泌器官的功能衰竭,与免疫介导的组织破坏有关。我们报告了一例罕见的 II 型多腺体综合征病例,该患者表现为卵巢早衰、桥本甲状腺炎和空蝶鞍,同时伴有分化型甲状腺癌的诊断。本例可能是首例报道的多腺体疾病患者伴发此种肿瘤的病例。

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