Limson B M, Garvez M D
Microbiology Section, Makati Medical Center, Manila, Philippines.
Clin Ther. 1990 Sep-Oct;12(5):436-9.
The subjects were adult hospitalized patients, 12 with pneumonia and eight with acute bronchitis. The patients with pneumonia received 500 mg of cefuroxime orally twice daily and the patients with bronchitis received 250 mg twice daily. Treatment lasted for ten days in responsive patients. The pathogens identified in the patients' sputum were Streptococcus pneumoniae, Klebsiella pneumoniae, Haemophilus influenzae, Enterobacter aerogenes, Staphylococcus aureus, or Branhamella catarrhalis. Clinical and bacteriologic cures were achieved in 11 of the 12 patients with pneumonia and in seven of the eight patients with bronchitis. It is concluded that cefuroxime axetil is safe and effective in the treatment of community-acquired pneumonia or acute bronchitis.
研究对象为成年住院患者，其中12例患有肺炎，8例患有急性支气管炎。肺炎患者口服头孢呋辛500毫克，每日两次；支气管炎患者口服250毫克，每日两次。有反应的患者治疗持续十天。在患者痰液中鉴定出的病原体有肺炎链球菌、肺炎克雷伯菌、流感嗜血杆菌、产气肠杆菌、金黄色葡萄球菌或卡他莫拉菌。12例肺炎患者中有11例实现了临床和细菌学治愈，8例支气管炎患者中有7例实现了临床和细菌学治愈。结论是头孢呋辛酯在治疗社区获得性肺炎或急性支气管炎方面安全有效。
