Ahmed M, Basit A
Department of Breast and General Surgery, University Hospital of North Staffordshire, Stoke-on-Trent, UK.
BMJ Case Rep. 2011 Jul 27;2011:bcr0220113825. doi: 10.1136/bcr.02.2011.3825.
A 47-year-old female presented with a 1-year history of 'eczematous change' to the right nipple. Bilateral mammography and ultrasound were entirely normal. Free hand biopsy demonstrated invasive adenocarcinoma of the nipple. The patient underwent a right-sided central segmentectomy and sentinel node biopsy. Histology demonstrated that the nipple was almost completely replaced by an invasive ductal carcinoma with a maximum diameter of 13 mm. Invasion of the underlying breast tissue was to a depth of 3 mm. A single sentinel lymph node demonstrated metastatic carcinoma. Her oestrogen receptor status was positive while HER-2 status was negative. The patient subsequently underwent right-sided axillary node clearance to level three nodes. All 17 nodes in the specimen were found to be within normal limits. She is scheduled to undergo radiotherapy, chemotherapy and hormonal treatment.
一名47岁女性因右侧乳头出现“湿疹样改变”1年就诊。双侧乳腺钼靶和超声检查均完全正常。徒手活检显示乳头浸润性腺癌。患者接受了右侧中央区段切除术和前哨淋巴结活检。组织学检查显示乳头几乎完全被最大直径为13毫米的浸润性导管癌取代。乳腺组织深层浸润深度为3毫米。单个前哨淋巴结显示有转移癌。她的雌激素受体状态为阳性，而HER-2状态为阴性。患者随后接受了右侧腋窝淋巴结清扫至三级淋巴结。标本中的所有17个淋巴结均在正常范围内。她计划接受放疗、化疗和激素治疗。
