乳腺癌的皮肤转移
Cutaneous metastases from breast carcinoma.
作者信息
Ahmed Muneer
机构信息
General and Breast Surgery, Shrewsbury and Telford NHS Trust, Telford, UK.
出版信息
BMJ Case Rep. 2011 Jul 28;2011:bcr0620114398. doi: 10.1136/bcr.06.2011.4398.
Abstract
We report the case of a rare presentation of cutaneous metastatic breast carcinoma. A 72-year-old lady who was previously fit and well presented with a 2-month history of a rash over the left breast. Clinically, in addition to the rash, she had a fixed tender mass of left supraclavicular fossa and left axillary lymph nodes. Punch biopsy of the skin demonstrated metastatic carcinoma and ultrasound of the left breast revealed a 9 mm irregular mass which was biopsied, demonstrating poorly differentiated grade III adenocarcinoma. She was oestrogen receptor negative but human epidermal growth factor receptor-2 positive on immunohistochemistry. She is currently undergoing chemotherapy with taxotere and herceptin.
摘要
我们报告了一例皮肤转移性乳腺癌的罕见病例。一名72岁的女性，既往身体健康，出现左侧乳房皮疹2个月。临床上，除皮疹外，她左侧锁骨上窝和左侧腋窝淋巴结有固定的压痛性肿块。皮肤穿刺活检显示为转移性癌，左侧乳房超声显示一个9毫米不规则肿块，经活检显示为低分化III级腺癌。免疫组化显示她雌激素受体阴性，但人表皮生长因子受体2阳性。她目前正在接受多西他赛和赫赛汀化疗。
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