Wiedemann H P, Matthay M A, Gillis C N
Department of Pulmonary Disease, Cleveland Clinic Foundation, Ohio.
Clin Chest Med. 1990 Dec;11(4):723-36.
Markers of endothelial cell damage or dysfunction may be sensitive probes for the detection of the earliest phases of acute lung injury and may be a guide to the severity of injury or response to therapy as well. Depressed lung metabolic function may contribute to the intrapulmonary or systemic pathophysiology of ARDS.
内皮细胞损伤或功能障碍的标志物可能是检测急性肺损伤最早阶段的敏感探针，也可能是损伤严重程度或对治疗反应的指导指标。肺代谢功能降低可能导致急性呼吸窘迫综合征的肺内或全身病理生理改变。
