Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
J Korean Med Sci. 2012 Jun;27(6):625-9. doi: 10.3346/jkms.2012.27.6.625. Epub 2012 May 26.
This prospective study surveyed the prevalence of peripheral arterial disease (PAD) in Korean patients with coronary arterial disease (CAD) or cerebrovascular disorder (CVD). From March 2010, 576 hospitalized patients in cardiovascular or stroke center were enrolled as the study group. Ankle-brachial index (ABI) was measured and the cut-off point for diagnosing PAD was ≤ 0.9 at rest. A total of 424 hospitalized patients in the Department of Surgery and aged ≥ 50 yr was enrolled as the control group. The prevalence of PAD was significantly higher in the study group than the control group (7.6% vs 1.7%; P < 0.001). To analyze the relationship of other vascular diseases and PAD, the patients were regrouped; group A (no CAD or CVD), group B (CAD only), group C (CVD only), and group D (CAD and CVD). Compared with group A, those with other vascular diseases (group B, C, D) had significantly higher prevalence of PAD, diabetes, dyslipidemia, renal insufficiency and claudication. The trend that patients with CAD or CVD are at risk of PAD is observed in this cross-sectional study in Koreans. Routine ABI measurement is recommended in these high-risk groups for early detection and proper management of PAD.
本前瞻性研究调查了韩国冠心病 (CAD) 或脑血管疾病 (CVD) 患者外周动脉疾病 (PAD) 的患病率。从 2010 年 3 月开始，心血管或中风中心的 576 名住院患者被纳入研究组。测量踝肱指数 (ABI)，诊断 PAD 的截断值为休息时≤0.9。外科和年龄≥50 岁的 424 名住院患者被纳入对照组。研究组 PAD 的患病率明显高于对照组 (7.6% vs 1.7%；P < 0.001)。为分析其他血管疾病与 PAD 的关系，将患者重新分组；A 组 (无 CAD 或 CVD)、B 组 (仅 CAD)、C 组 (仅 CVD) 和 D 组 (CAD 和 CVD)。与 A 组相比，其他血管疾病 (B、C、D 组) 患者 PAD、糖尿病、血脂异常、肾功能不全和跛行的患病率明显更高。本横断面研究观察到韩国 CAD 或 CVD 患者存在 PAD 风险。建议在这些高危人群中常规测量 ABI，以早期发现和适当管理 PAD。
