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[人唾液中口腔链球菌潜在受体的电泳分析]

[Electrophoretic analysis of potential receptors for oral streptococci in human saliva].

作者信息

Bergmann J E, Gülzow H J, Köpsell R

机构信息

Klinik und Poliklinik für Zahn-, Mund- und Kieferkrankheiten der Universität Hamburg.

出版信息

Dtsch Zahnarztl Z. 1990 Nov;45(11):733-6.

PMID:2269095
Abstract

Initial adhesion of oral streptococci occurs at specific binding sites present in the dental pellicle. These receptors are salivary proteins and glycoproteins which by necessity possess affinity to dental enamel as well as to the adhering microorganism. By gel electrophoresis and immunoblotting, five such proteins were shown which bound to hydroxyapatite and oral streptococci. Information on the molecular events of initial adhesion to dental surfaces by oral microorganisms may possibly open new avenues in caries prevention.

摘要

口腔链球菌的初始黏附发生在牙菌斑中存在的特定结合位点。这些受体是唾液蛋白和糖蛋白,它们必然对牙釉质以及黏附的微生物具有亲和力。通过凝胶电泳和免疫印迹,显示出五种这样的与羟基磷灰石和口腔链球菌结合的蛋白质。关于口腔微生物对牙齿表面初始黏附的分子事件的信息可能会为龋齿预防开辟新途径。

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