Cukurova Ibrahim, Gumussoy Murat, Yaz Aytekin, Bayol Umit, Yigitbasi Orhan Gazi
Department of Otolaryngology and Head and Neck Surgery, the Ministry of Health Izmir Tepecik Training and Research Hospital, Izmir, 35120, Turkey.
J Med Case Rep. 2012 Jun 12;6:147. doi: 10.1186/1752-1947-6-147.
Teratoma refers to a neoplasm that recapitulates all three germ layers. Teratomas may be histologically mature and oncologically benign. Teratomas may also be histologically immature while being oncologically benign, or they may harbor malignant components and have the potential to exhibit an aggressive biological behavior. Teratomas of the head and neck are extremely rare and usually present in the neonatal period. As a general rule, pediatric teratomas of the head and neck tend to be oncologically benign, whereas adult teratomas tend to be histologically and oncologically malignant. Most of these teratomas are found in the cervical region and nasopharynx. Calcification within the mass is often evident.
A 27-year-old Caucasian man complaining of a nasal obstruction was admitted to our clinic in January 2006. A transnasal endoscopic examination revealed a mass arising from the nasal septum which was completely removed using an endoscopic approach. Histologically, it was determined to be a benign teratoma.
Herein, we present a rare case, along with a review of the related literature, in order to emphasize that a benign teratoma of the nasal septum should not be ignored.
畸胎瘤是一种再现所有三个胚层的肿瘤。畸胎瘤在组织学上可能成熟且在肿瘤学上为良性。畸胎瘤在组织学上也可能不成熟但在肿瘤学上为良性,或者它们可能含有恶性成分并有可能表现出侵袭性生物学行为。头颈部畸胎瘤极为罕见,通常在新生儿期出现。一般来说,头颈部小儿畸胎瘤在肿瘤学上往往为良性,而成人畸胎瘤在组织学和肿瘤学上往往为恶性。这些畸胎瘤大多见于颈部区域和鼻咽部。肿块内的钙化通常很明显。
一名27岁的白人男性因鼻塞于2006年1月入住我院。经鼻内镜检查发现鼻中隔有一肿块,采用内镜方法将其完全切除。组织学检查确定为良性畸胎瘤。
在此,我们报告一例罕见病例,并对相关文献进行综述,以强调鼻中隔良性畸胎瘤不应被忽视。