Division of Pediatric Nephrology and Hypertension, Department of Pediatrics, Maimonides Medical Center, 977 48th Street, Brooklyn, NY 11219, USA.
Pediatr Nephrol. 2013 Mar;28(3):401-8. doi: 10.1007/s00467-012-2215-8. Epub 2012 Jun 13.
Data on neurocognitive function in hypertensive children are limited. In this review, we summarize recent preliminary, early studies that suggest that children with elevated blood pressure demonstrate evidence of worse performance on direct neurocognitive testing, as well as evidence of executive dysfunction based on parent ratings, compared with matched normotensive comparison groups. Furthermore, hypertensive children may have increased prevalence of learning disabilities as well as a blunted cerebrovascular reactivity compared with normotensive controls. Larger, prospective studies are needed to confirm and further explore these emerging but preliminary findings.
高血压儿童的神经认知功能数据有限。在这篇综述中,我们总结了最近的初步、早期研究,这些研究表明,与匹配的正常血压对照组相比,血压升高的儿童在直接神经认知测试中的表现更差,以及基于家长评分的执行功能障碍的证据。此外,与正常血压对照相比,高血压儿童可能更普遍存在学习障碍,以及脑血管反应性迟钝。需要更大规模的前瞻性研究来证实和进一步探讨这些新出现但初步的发现。